Prenylated indole diketopiperazine alkaloids, spiro-
نویسنده
چکیده
Peroxy-containing metabolitesare an interesting group amongbiological active natural compounds. These metabolites contain a peroxide group (-O-O-) in which each oxygen atom is bonded to the other oxygen an to another atom. β-Oxygen in hydroperoxide group is considered as moreactive.Present review describes research on more than 100 natural hydroperoxidesand rare acyclic peroxides isolated from plants, algae, and fungi. Intensive searches for new classes of biologicallyactive metabolites produced by terrestrial and marine origin have resulted in the discovery of dozens of compounds possessing high antimalarial,antibacterial, cytotoxic, and other pharmacological activitiesas an important source of leads for drug discovery. Received date: 11-08-2015; Accepted date: 19-09-2015; Published date: 21-09-2015
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